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Patterns of Recombination in HIV-1M Are Influenced by Selection Disfavouring the Survival of Recombinants with Disrupted Genomic RNA and Protein Structures

Genetic recombination is a major contributor to the ongoing diversification of HIV. It is clearly apparent that across the HIV-genome there are defined recombination hot and cold spots which tend to co-localise both with genomic secondary structures and with either inter-gene boundaries or intra-gen...

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Detalles Bibliográficos
Autores principales: Golden, Michael, Muhire, Brejnev M., Semegni, Yves, Martin, Darren P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061080/
https://www.ncbi.nlm.nih.gov/pubmed/24936864
http://dx.doi.org/10.1371/journal.pone.0100400