On the necessity of dissecting sequence similarity scores into segment-specific contributions for inferring protein homology, function prediction and annotation

BACKGROUND: Protein sequence similarities to any types of non-globular segments (coiled coils, low complexity regions, transmembrane regions, long loops, etc. where either positional sequence conservation is the result of a very simple, physically induced pattern or rather integral sequence properti...

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Detalles Bibliográficos
Autores principales: Wong, Wing-Cheong, Maurer-Stroh, Sebastian, Eisenhaber, Birgit, Eisenhaber, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061105/
https://www.ncbi.nlm.nih.gov/pubmed/24890864
http://dx.doi.org/10.1186/1471-2105-15-166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061105/
https://www.ncbi.nlm.nih.gov/pubmed/24890864
http://dx.doi.org/10.1186/1471-2105-15-166

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