Management options for the treatment of benign prostatic hyperplasia with or without erectile dysfunction: a focus on tadalafil and patient considerations

Lower urinary tract symptoms (LUTS) and erectile dysfunction increase with age. Several studies have identified a true association between these two disorders. Basic research studies have shown a significant decrease in the nitric oxide/cyclic guanosine monophosphate pathway with age that leads to d...

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Detalles Bibliográficos
Autores principales: Alsaikhan, Bader, Alrabeeah, Khalid, Carrier, Serge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061160/
https://www.ncbi.nlm.nih.gov/pubmed/24959092
http://dx.doi.org/10.2147/IJGM.S40216
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author Alsaikhan, Bader
Alrabeeah, Khalid
Carrier, Serge
author_facet Alsaikhan, Bader
Alrabeeah, Khalid
Carrier, Serge
author_sort Alsaikhan, Bader
collection PubMed
description Lower urinary tract symptoms (LUTS) and erectile dysfunction increase with age. Several studies have identified a true association between these two disorders. Basic research studies have shown a significant decrease in the nitric oxide/cyclic guanosine monophosphate pathway with age that leads to decreased relaxation of the bladder wall and prostate and worsening LUTS. In this review article, we will focus on the potential use and clinical significance of phosphodiesterase-5 inhibitors in the treatment of LUTS secondary to benign prostate hyperplasia.
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spelling pubmed-40611602014-06-23 Management options for the treatment of benign prostatic hyperplasia with or without erectile dysfunction: a focus on tadalafil and patient considerations Alsaikhan, Bader Alrabeeah, Khalid Carrier, Serge Int J Gen Med Review Lower urinary tract symptoms (LUTS) and erectile dysfunction increase with age. Several studies have identified a true association between these two disorders. Basic research studies have shown a significant decrease in the nitric oxide/cyclic guanosine monophosphate pathway with age that leads to decreased relaxation of the bladder wall and prostate and worsening LUTS. In this review article, we will focus on the potential use and clinical significance of phosphodiesterase-5 inhibitors in the treatment of LUTS secondary to benign prostate hyperplasia. Dove Medical Press 2014-06-12 /pmc/articles/PMC4061160/ /pubmed/24959092 http://dx.doi.org/10.2147/IJGM.S40216 Text en © 2014 Alsaikhan et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Review
Alsaikhan, Bader
Alrabeeah, Khalid
Carrier, Serge
Management options for the treatment of benign prostatic hyperplasia with or without erectile dysfunction: a focus on tadalafil and patient considerations
title Management options for the treatment of benign prostatic hyperplasia with or without erectile dysfunction: a focus on tadalafil and patient considerations
title_full Management options for the treatment of benign prostatic hyperplasia with or without erectile dysfunction: a focus on tadalafil and patient considerations
title_fullStr Management options for the treatment of benign prostatic hyperplasia with or without erectile dysfunction: a focus on tadalafil and patient considerations
title_full_unstemmed Management options for the treatment of benign prostatic hyperplasia with or without erectile dysfunction: a focus on tadalafil and patient considerations
title_short Management options for the treatment of benign prostatic hyperplasia with or without erectile dysfunction: a focus on tadalafil and patient considerations
title_sort management options for the treatment of benign prostatic hyperplasia with or without erectile dysfunction: a focus on tadalafil and patient considerations
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061160/
https://www.ncbi.nlm.nih.gov/pubmed/24959092
http://dx.doi.org/10.2147/IJGM.S40216
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