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Emerging molecular targets in oncology: clinical potential of MET/hepatocyte growth-factor inhibitors

The MET/hepatocyte growth-factor (HGF) signaling pathway plays a key role in the processes of embryogenesis, wound healing, and organ regeneration. Aberrant activation of MET/HGF occurs through multiple mechanisms including gene amplification, mutation, protein overexpression, and abnormal gene spli...

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Detalles Bibliográficos
Autores principales:	Smyth, Elizabeth C, Sclafani, Francesco, Cunningham, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2014
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061165/ https://www.ncbi.nlm.nih.gov/pubmed/24959087 http://dx.doi.org/10.2147/OTT.S44941

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