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Emphysema and COPD in a young woman

A 28-year old woman presented with a progressive cough and breathlessness. She had a family history of early onset COPD. Spirometry demonstrated airflow obstruction with no reversibility. An HRCT showed extensive centrolobular emphysema with an upper lobe predominance. Blood tests including an Alpha...

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Detalles Bibliográficos
Autores principales: Conroy, Kevin, Miller, Graham, Shipley, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061421/
https://www.ncbi.nlm.nih.gov/pubmed/26029541
http://dx.doi.org/10.1016/j.rmcr.2014.03.003
Descripción
Sumario:A 28-year old woman presented with a progressive cough and breathlessness. She had a family history of early onset COPD. Spirometry demonstrated airflow obstruction with no reversibility. An HRCT showed extensive centrolobular emphysema with an upper lobe predominance. Blood tests including an Alpha – 1 Antitrypsin level were normal.