Two patients with new granulomatous lung lesions during treatment of Crohn's disease

Two patients with granulomatous lung lesions thought to be related to Crohn's disease (CD) are reported. Patient 1 was a 43-year-old man who was diagnosed with CD at age 11 years. He developed a fever in the 38 °C, and a chest X-ray and CT scan showed infiltrates with air bronchograms in the ri...

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Detalles Bibliográficos
Autores principales: Takeda, Satoshi, Akagi, Takanori, Miyazaki, Hiroyuki, Kodama, Masaru, Yamamoto, Satoshi, Beppu, Takahiro, Nagahama, Takashi, Matsui, Toshiyuki, Watanabe, Kentaro, Nagata, Nobuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061430/
https://www.ncbi.nlm.nih.gov/pubmed/26029529
http://dx.doi.org/10.1016/j.rmcr.2014.02.002
Descripción
Sumario:Two patients with granulomatous lung lesions thought to be related to Crohn's disease (CD) are reported. Patient 1 was a 43-year-old man who was diagnosed with CD at age 11 years. He developed a fever in the 38 °C, and a chest X-ray and CT scan showed infiltrates with air bronchograms in the right upper lobe and left lingular segment. Transbronchial lung biopsy (TBLB) revealed granulomatous lesions. Patient 2 was a 76-year-old woman who was diagnosed with CD at age 44 years. Chest CT showed infiltrates and nodular shadows in both lung fields. Video-assisted thoracoscopic surgery (VATS) in June 2012 revealed granulomatous lesions. Tuberculosis, fungal infections, drug-induced lung disorder, and sarcoidosis were ruled out as a cause of the granulomatous lesions in both patients. The aetiology was thought to be CD.

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