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Two patients with new granulomatous lung lesions during treatment of Crohn's disease

Two patients with granulomatous lung lesions thought to be related to Crohn's disease (CD) are reported. Patient 1 was a 43-year-old man who was diagnosed with CD at age 11 years. He developed a fever in the 38 °C, and a chest X-ray and CT scan showed infiltrates with air bronchograms in the ri...

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Autores principales: Takeda, Satoshi, Akagi, Takanori, Miyazaki, Hiroyuki, Kodama, Masaru, Yamamoto, Satoshi, Beppu, Takahiro, Nagahama, Takashi, Matsui, Toshiyuki, Watanabe, Kentaro, Nagata, Nobuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061430/
https://www.ncbi.nlm.nih.gov/pubmed/26029529
http://dx.doi.org/10.1016/j.rmcr.2014.02.002
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author Takeda, Satoshi
Akagi, Takanori
Miyazaki, Hiroyuki
Kodama, Masaru
Yamamoto, Satoshi
Beppu, Takahiro
Nagahama, Takashi
Matsui, Toshiyuki
Watanabe, Kentaro
Nagata, Nobuhiko
author_facet Takeda, Satoshi
Akagi, Takanori
Miyazaki, Hiroyuki
Kodama, Masaru
Yamamoto, Satoshi
Beppu, Takahiro
Nagahama, Takashi
Matsui, Toshiyuki
Watanabe, Kentaro
Nagata, Nobuhiko
author_sort Takeda, Satoshi
collection PubMed
description Two patients with granulomatous lung lesions thought to be related to Crohn's disease (CD) are reported. Patient 1 was a 43-year-old man who was diagnosed with CD at age 11 years. He developed a fever in the 38 °C, and a chest X-ray and CT scan showed infiltrates with air bronchograms in the right upper lobe and left lingular segment. Transbronchial lung biopsy (TBLB) revealed granulomatous lesions. Patient 2 was a 76-year-old woman who was diagnosed with CD at age 44 years. Chest CT showed infiltrates and nodular shadows in both lung fields. Video-assisted thoracoscopic surgery (VATS) in June 2012 revealed granulomatous lesions. Tuberculosis, fungal infections, drug-induced lung disorder, and sarcoidosis were ruled out as a cause of the granulomatous lesions in both patients. The aetiology was thought to be CD.
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spelling pubmed-40614302014-10-15 Two patients with new granulomatous lung lesions during treatment of Crohn's disease Takeda, Satoshi Akagi, Takanori Miyazaki, Hiroyuki Kodama, Masaru Yamamoto, Satoshi Beppu, Takahiro Nagahama, Takashi Matsui, Toshiyuki Watanabe, Kentaro Nagata, Nobuhiko Respir Med Case Rep Case Report Two patients with granulomatous lung lesions thought to be related to Crohn's disease (CD) are reported. Patient 1 was a 43-year-old man who was diagnosed with CD at age 11 years. He developed a fever in the 38 °C, and a chest X-ray and CT scan showed infiltrates with air bronchograms in the right upper lobe and left lingular segment. Transbronchial lung biopsy (TBLB) revealed granulomatous lesions. Patient 2 was a 76-year-old woman who was diagnosed with CD at age 44 years. Chest CT showed infiltrates and nodular shadows in both lung fields. Video-assisted thoracoscopic surgery (VATS) in June 2012 revealed granulomatous lesions. Tuberculosis, fungal infections, drug-induced lung disorder, and sarcoidosis were ruled out as a cause of the granulomatous lesions in both patients. The aetiology was thought to be CD. Elsevier 2014-02-22 /pmc/articles/PMC4061430/ /pubmed/26029529 http://dx.doi.org/10.1016/j.rmcr.2014.02.002 Text en © 2014 The Authors http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/).
spellingShingle Case Report
Takeda, Satoshi
Akagi, Takanori
Miyazaki, Hiroyuki
Kodama, Masaru
Yamamoto, Satoshi
Beppu, Takahiro
Nagahama, Takashi
Matsui, Toshiyuki
Watanabe, Kentaro
Nagata, Nobuhiko
Two patients with new granulomatous lung lesions during treatment of Crohn's disease
title Two patients with new granulomatous lung lesions during treatment of Crohn's disease
title_full Two patients with new granulomatous lung lesions during treatment of Crohn's disease
title_fullStr Two patients with new granulomatous lung lesions during treatment of Crohn's disease
title_full_unstemmed Two patients with new granulomatous lung lesions during treatment of Crohn's disease
title_short Two patients with new granulomatous lung lesions during treatment of Crohn's disease
title_sort two patients with new granulomatous lung lesions during treatment of crohn's disease
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061430/
https://www.ncbi.nlm.nih.gov/pubmed/26029529
http://dx.doi.org/10.1016/j.rmcr.2014.02.002
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