Cargando…

Two cases of culture proven Mycobacterium tuberculosis presenting with a broad-complex tachycardia and non-caseating granulomas

Tuberculosis is a leading cause of death worldwide. It affects pulmonary and extra-pulmonary sites with a multitude of differing presentations. In this report, we describe two cases in which TB causes myopericarditis and presents with a broad-complex tachycardia that did not respond typically to sta...

Descripción completa

Detalles Bibliográficos
Autores principales: Farah, Z., Beasley, V.E., Berry, M., Coker, R.K., Kon, O.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061437/
https://www.ncbi.nlm.nih.gov/pubmed/26029538
http://dx.doi.org/10.1016/j.rmcr.2013.10.003
_version_ 1782321492087799808
author Farah, Z.
Beasley, V.E.
Berry, M.
Coker, R.K.
Kon, O.M.
author_facet Farah, Z.
Beasley, V.E.
Berry, M.
Coker, R.K.
Kon, O.M.
author_sort Farah, Z.
collection PubMed
description Tuberculosis is a leading cause of death worldwide. It affects pulmonary and extra-pulmonary sites with a multitude of differing presentations. In this report, we describe two cases in which TB causes myopericarditis and presents with a broad-complex tachycardia that did not respond typically to standard anti-arrhythmic therapy; a very rare presentation with limited description in the literature. Both patients required extensive investigation culminating in identifying lymph nodes amenable to biopsy under endobronchial ultrasound guidance. It was not until both patients received anti-tuberculous chemotherapy alongside anti-arrhythmic management that any improvement to their condition was witnessed. Therefore, we recommend that the clinician should have a high index of suspicion for TB in any patient presenting with a broad-complex tachycardia that is not responding to standard first line management, especially if the patient is from a high risk background. We recommend an active diagnostic pursuit, and lymph node biopsy under endobronchial ultrasound guidance.
format Online
Article
Text
id pubmed-4061437
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-40614372014-10-15 Two cases of culture proven Mycobacterium tuberculosis presenting with a broad-complex tachycardia and non-caseating granulomas Farah, Z. Beasley, V.E. Berry, M. Coker, R.K. Kon, O.M. Respir Med Case Rep Case Report Tuberculosis is a leading cause of death worldwide. It affects pulmonary and extra-pulmonary sites with a multitude of differing presentations. In this report, we describe two cases in which TB causes myopericarditis and presents with a broad-complex tachycardia that did not respond typically to standard anti-arrhythmic therapy; a very rare presentation with limited description in the literature. Both patients required extensive investigation culminating in identifying lymph nodes amenable to biopsy under endobronchial ultrasound guidance. It was not until both patients received anti-tuberculous chemotherapy alongside anti-arrhythmic management that any improvement to their condition was witnessed. Therefore, we recommend that the clinician should have a high index of suspicion for TB in any patient presenting with a broad-complex tachycardia that is not responding to standard first line management, especially if the patient is from a high risk background. We recommend an active diagnostic pursuit, and lymph node biopsy under endobronchial ultrasound guidance. Elsevier 2014-04-16 /pmc/articles/PMC4061437/ /pubmed/26029538 http://dx.doi.org/10.1016/j.rmcr.2013.10.003 Text en © 2013 The Authors http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/).
spellingShingle Case Report
Farah, Z.
Beasley, V.E.
Berry, M.
Coker, R.K.
Kon, O.M.
Two cases of culture proven Mycobacterium tuberculosis presenting with a broad-complex tachycardia and non-caseating granulomas
title Two cases of culture proven Mycobacterium tuberculosis presenting with a broad-complex tachycardia and non-caseating granulomas
title_full Two cases of culture proven Mycobacterium tuberculosis presenting with a broad-complex tachycardia and non-caseating granulomas
title_fullStr Two cases of culture proven Mycobacterium tuberculosis presenting with a broad-complex tachycardia and non-caseating granulomas
title_full_unstemmed Two cases of culture proven Mycobacterium tuberculosis presenting with a broad-complex tachycardia and non-caseating granulomas
title_short Two cases of culture proven Mycobacterium tuberculosis presenting with a broad-complex tachycardia and non-caseating granulomas
title_sort two cases of culture proven mycobacterium tuberculosis presenting with a broad-complex tachycardia and non-caseating granulomas
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061437/
https://www.ncbi.nlm.nih.gov/pubmed/26029538
http://dx.doi.org/10.1016/j.rmcr.2013.10.003
work_keys_str_mv AT farahz twocasesofcultureprovenmycobacteriumtuberculosispresentingwithabroadcomplextachycardiaandnoncaseatinggranulomas
AT beasleyve twocasesofcultureprovenmycobacteriumtuberculosispresentingwithabroadcomplextachycardiaandnoncaseatinggranulomas
AT berrym twocasesofcultureprovenmycobacteriumtuberculosispresentingwithabroadcomplextachycardiaandnoncaseatinggranulomas
AT cokerrk twocasesofcultureprovenmycobacteriumtuberculosispresentingwithabroadcomplextachycardiaandnoncaseatinggranulomas
AT konom twocasesofcultureprovenmycobacteriumtuberculosispresentingwithabroadcomplextachycardiaandnoncaseatinggranulomas