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Repression of phosphoinositide-dependent protein kinase 1 expression by ciglitazone via Egr-1 represents a new approach for inhibition of lung cancer cell growth

BACKGROUND: Peroxisome proliferator-activated receptors gamma (PPARγ) ligands have been shown to inhibit the growth of non-small cell lung cancer (NSCLC) cells. However, the mechanisms underlying this effect remain incompletely elucidated. METHODS: Cell proliferation and apoptosis were measured by c...

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Detalles Bibliográficos
Autores principales:	Hann, SWei Sunny, Tang, Qing, Zheng, Fang, Zhao, Shunyu, Chen, Jianping, Wang, ZhiYu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061523/ https://www.ncbi.nlm.nih.gov/pubmed/24925061 http://dx.doi.org/10.1186/1476-4598-13-149

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