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Activation of K(2)P channel–TREK1 mediates the neuroprotection induced by sevoflurane preconditioning
BACKGROUND: Preconditioning with volatile anaesthetic agents induces tolerance to focal cerebral ischaemia, although the underlying mechanisms have not been clearly defined. The present study analyses whether TREK-1, a two-pore domain K(+) channel and target for volatile anaesthetics, plays a role i...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062297/ https://www.ncbi.nlm.nih.gov/pubmed/24154701 http://dx.doi.org/10.1093/bja/aet338 |