Targeting the Wnt/β-Catenin Signaling Pathway in Liver Cancer Stem Cells and Hepatocellular Carcinoma Cell Lines with FH535

Activation of the Wnt/β-catenin pathway has been observed in at least 1/3 of hepatocellular carcinomas (HCC), and a significant number of these have mutations in the β-catenin gene. Therefore, effective inhibition of this pathway could provide a novel method to treat HCC. The purposed of this study...

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Detalles Bibliográficos
Autores principales: Gedaly, Roberto, Galuppo, Roberto, Daily, Michael F., Shah, Malay, Maynard, Erin, Chen, Changguo, Zhang, Xiping, Esser, Karyn A., Cohen, Donald A., Evers, B. Mark, Jiang, Jieyun, Spear, Brett T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062395/
https://www.ncbi.nlm.nih.gov/pubmed/24940873
http://dx.doi.org/10.1371/journal.pone.0099272

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