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Contribution of a Non-β-Cell Source to β-Cell Mass during Pregnancy
β-cell mass in the pancreas increases significantly during pregnancy as an adaptation to maternal insulin resistance. Lineage tracing studies in rodents have presented conflicting evidence on the role of cell duplication in the formation of new β-cells during gestation, while recent human data sugge...
Autores principales: | Toselli, Chiara, Hyslop, Colin M., Hughes, Martha, Natale, David R., Santamaria, Pere, Huang, Carol T. L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062500/ https://www.ncbi.nlm.nih.gov/pubmed/24940737 http://dx.doi.org/10.1371/journal.pone.0100398 |
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