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Administration of angiotensin II and a bradykinin B2 receptor blocker in midpregnancy impairs gestational outcome in guinea pigs

BACKGROUND: The opposing renin-angiotensin system (RAS) and kallikrein-kinin system (KKS) are upregulated in pregnancy and localize in the utero-placental unit. To test their participation as counter-regulators, circulating angiotensin II (AII) was exogenously elevated and the bradykinin B2 receptor...

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Detalles Bibliográficos
Autores principales: Valdés, Gloria, Schneider, Daniela, Corthorn, Jenny, Ortíz, Rita, Acuña, Stephanie, Padilla, Oslando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062647/
https://www.ncbi.nlm.nih.gov/pubmed/24893657
http://dx.doi.org/10.1186/1477-7827-12-49

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