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Estimating the optimal threshold for a diagnostic biomarker in case of complex biomarker distributions
BACKGROUND: Estimating the optimal threshold (and especially the confidence interval) of a quantitative biomarker to be used as a diagnostic test is essential for medical decision-making. This is often done with simple methods that are not always reliable. More advanced methods work well but only fo...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062774/ https://www.ncbi.nlm.nih.gov/pubmed/24927622 http://dx.doi.org/10.1186/1472-6947-14-53 |