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Estimating the optimal threshold for a diagnostic biomarker in case of complex biomarker distributions

BACKGROUND: Estimating the optimal threshold (and especially the confidence interval) of a quantitative biomarker to be used as a diagnostic test is essential for medical decision-making. This is often done with simple methods that are not always reliable. More advanced methods work well but only fo...

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Detalles Bibliográficos
Autores principales: Subtil, Fabien, Rabilloud, Muriel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062774/
https://www.ncbi.nlm.nih.gov/pubmed/24927622
http://dx.doi.org/10.1186/1472-6947-14-53