Spatial Characterization of Hot Melt Extruded Dispersion Systems Using Thermal Atomic Force Microscopy Methods: The Effects of Processing Parameters on Phase Separation

PURPOSE: In this study we explore the use of nano-scale localized thermal analysis (LTA) and transition temperature microcopy (TTM) as a novel combined approach to studying phase separation in HME dispersions of cyclosporine A in Eudragit EPO. METHODS: Modulated temperature differential scanning cal...

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Detalles Bibliográficos
Autores principales: Moffat, Jonathan G., Qi, Sheng, Craig, Duncan Q. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062809/
https://www.ncbi.nlm.nih.gov/pubmed/24554116
http://dx.doi.org/10.1007/s11095-013-1279-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062809/
https://www.ncbi.nlm.nih.gov/pubmed/24554116
http://dx.doi.org/10.1007/s11095-013-1279-x

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