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Spatial Characterization of Hot Melt Extruded Dispersion Systems Using Thermal Atomic Force Microscopy Methods: The Effects of Processing Parameters on Phase Separation

PURPOSE: In this study we explore the use of nano-scale localized thermal analysis (LTA) and transition temperature microcopy (TTM) as a novel combined approach to studying phase separation in HME dispersions of cyclosporine A in Eudragit EPO. METHODS: Modulated temperature differential scanning cal...

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Detalles Bibliográficos
Autores principales:	Moffat, Jonathan G., Qi, Sheng, Craig, Duncan Q. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2014
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062809/ https://www.ncbi.nlm.nih.gov/pubmed/24554116 http://dx.doi.org/10.1007/s11095-013-1279-x

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