Inhibition of Janus kinase signaling during controlled mechanical ventilation prevents ventilation-induced diaphragm dysfunction

Controlled mechanical ventilation (CMV) is associated with the development of diaphragm atrophy and contractile dysfunction, and respiratory muscle weakness is thought to contribute significantly to delayed weaning of patients. Therefore, therapeutic strategies for preventing these processes may hav...

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Detalles Bibliográficos
Autores principales: Smith, Ira J., Godinez, Guillermo L., Singh, Baljit K., McCaughey, Kelly M., Alcantara, Raniel R., Gururaja, Tarikere, Ho, Melissa S., Nguyen, Henry N., Friera, Annabelle M., White, Kathy A., McLaughlin, John R., Hansen, Derek, Romero, Jason M., Baltgalvis, Kristen A., Claypool, Mark D., Li, Wei, Lang, Wayne, Yam, George C., Gelman, Marina S., Ding, Rongxian, Yung, Stephanie L., Creger, Daniel P., Chen, Yan, Singh, Rajinder, Smuder, Ashley J., Wiggs, Michael P., Kwon, Oh-Sung, Sollanek, Kurt J., Powers, Scott K., Masuda, Esteban S., Taylor, Vanessa C., Payan, Donald G., Kinoshita, Taisei, Kinsella, Todd M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2014
Materias:
Research Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062832/
https://www.ncbi.nlm.nih.gov/pubmed/24671708
http://dx.doi.org/10.1096/fj.13-244210

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062832/
https://www.ncbi.nlm.nih.gov/pubmed/24671708
http://dx.doi.org/10.1096/fj.13-244210

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