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Assessment of T2-Weighted Coronal Magnetic Resonance Images in the Investigation of Pituitary Lesions

Magnetic resonance imaging is the most important diagnostic method in the investigation of the pituitary lesions. Our aim is to determine whether T2-weighted coronal images may be helpful in the evaluation of the pituitary gland with suspected pituitary adenomas. One hundred and sixty-seven patients...

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Autores principales: Yuksekkaya, Ruken, Aggunlu, Levent, Oner, Yusuf, Celik, Halil, Akpek, Sergin, Celikyay, Fatih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062849/
https://www.ncbi.nlm.nih.gov/pubmed/24977139
http://dx.doi.org/10.1155/2014/650926
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author Yuksekkaya, Ruken
Aggunlu, Levent
Oner, Yusuf
Celik, Halil
Akpek, Sergin
Celikyay, Fatih
author_facet Yuksekkaya, Ruken
Aggunlu, Levent
Oner, Yusuf
Celik, Halil
Akpek, Sergin
Celikyay, Fatih
author_sort Yuksekkaya, Ruken
collection PubMed
description Magnetic resonance imaging is the most important diagnostic method in the investigation of the pituitary lesions. Our aim is to determine whether T2-weighted coronal images may be helpful in the evaluation of the pituitary gland with suspected pituitary adenomas. One hundred and sixty-seven patients were examined prospectively with T2-weighted coronal and T1-weighted coronal images enhanced with intravenous contrast material. The images were evaluated for the presence, the size, the location, and the ancillary signs including sellar floor erosion or ballooning, infindibulary deviation, convexity of the superior border of the gland, diffuse enlargement of the gland, and the invasion of the cavenous sinuses on both images. In forty-six (28%) patients lesions were revealed on both sequences. In twenty-one (12%) patients the lesions that were revealed on the T1-weighted images were not detected on the T2-weighted images. Positive predictive value, negative predictive value, sensitivity, specificity, and diagnostic accuracy rates of T2-weighted coronal images on the detection of the presence of lesions were 100%, 17.4%, 68.7%, 100%, and 87.4%, respectively. Both T2-weighted coronal and T1-weighted coronal images enhanced with intravenous gadolinium-based contrast material are important in the diagnosis of pituitary adenomas. T2-weighted coronal images could be used as a screening tool for the primary evaluation of the pituitary gland.
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spelling pubmed-40628492014-06-29 Assessment of T2-Weighted Coronal Magnetic Resonance Images in the Investigation of Pituitary Lesions Yuksekkaya, Ruken Aggunlu, Levent Oner, Yusuf Celik, Halil Akpek, Sergin Celikyay, Fatih ISRN Radiol Clinical Study Magnetic resonance imaging is the most important diagnostic method in the investigation of the pituitary lesions. Our aim is to determine whether T2-weighted coronal images may be helpful in the evaluation of the pituitary gland with suspected pituitary adenomas. One hundred and sixty-seven patients were examined prospectively with T2-weighted coronal and T1-weighted coronal images enhanced with intravenous contrast material. The images were evaluated for the presence, the size, the location, and the ancillary signs including sellar floor erosion or ballooning, infindibulary deviation, convexity of the superior border of the gland, diffuse enlargement of the gland, and the invasion of the cavenous sinuses on both images. In forty-six (28%) patients lesions were revealed on both sequences. In twenty-one (12%) patients the lesions that were revealed on the T1-weighted images were not detected on the T2-weighted images. Positive predictive value, negative predictive value, sensitivity, specificity, and diagnostic accuracy rates of T2-weighted coronal images on the detection of the presence of lesions were 100%, 17.4%, 68.7%, 100%, and 87.4%, respectively. Both T2-weighted coronal and T1-weighted coronal images enhanced with intravenous gadolinium-based contrast material are important in the diagnosis of pituitary adenomas. T2-weighted coronal images could be used as a screening tool for the primary evaluation of the pituitary gland. Hindawi Publishing Corporation 2014-03-23 /pmc/articles/PMC4062849/ /pubmed/24977139 http://dx.doi.org/10.1155/2014/650926 Text en Copyright © 2014 Ruken Yuksekkaya et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Study
Yuksekkaya, Ruken
Aggunlu, Levent
Oner, Yusuf
Celik, Halil
Akpek, Sergin
Celikyay, Fatih
Assessment of T2-Weighted Coronal Magnetic Resonance Images in the Investigation of Pituitary Lesions
title Assessment of T2-Weighted Coronal Magnetic Resonance Images in the Investigation of Pituitary Lesions
title_full Assessment of T2-Weighted Coronal Magnetic Resonance Images in the Investigation of Pituitary Lesions
title_fullStr Assessment of T2-Weighted Coronal Magnetic Resonance Images in the Investigation of Pituitary Lesions
title_full_unstemmed Assessment of T2-Weighted Coronal Magnetic Resonance Images in the Investigation of Pituitary Lesions
title_short Assessment of T2-Weighted Coronal Magnetic Resonance Images in the Investigation of Pituitary Lesions
title_sort assessment of t2-weighted coronal magnetic resonance images in the investigation of pituitary lesions
topic Clinical Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062849/
https://www.ncbi.nlm.nih.gov/pubmed/24977139
http://dx.doi.org/10.1155/2014/650926
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