Rapid brain death caused by a cerebellar abscess with Fusobacterium nucleatum in a young man with drug abuse: a case report

BACKGROUND: Fusobacterium nucleatum is a strict anaerobic microorganism that causes disease entities such as periodontal and soft tissue abscesses, pulmonary and intraabdominal infections and very rarely intracerebral infections. CASE PRESENTATION: Here, we report the rare case of a previously healt...

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Autores principales: Hischebeth, Gunnar TR, Keil, Vera C, Gentil, Katrin, Boström, Azize, Kuchelmeister, Klaus, Bekeredjian-Ding, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062896/
https://www.ncbi.nlm.nih.gov/pubmed/24915846
http://dx.doi.org/10.1186/1756-0500-7-353
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author Hischebeth, Gunnar TR
Keil, Vera C
Gentil, Katrin
Boström, Azize
Kuchelmeister, Klaus
Bekeredjian-Ding, Isabelle
author_facet Hischebeth, Gunnar TR
Keil, Vera C
Gentil, Katrin
Boström, Azize
Kuchelmeister, Klaus
Bekeredjian-Ding, Isabelle
author_sort Hischebeth, Gunnar TR
collection PubMed
description BACKGROUND: Fusobacterium nucleatum is a strict anaerobic microorganism that causes disease entities such as periodontal and soft tissue abscesses, pulmonary and intraabdominal infections and very rarely intracerebral infections. CASE PRESENTATION: Here, we report the rare case of a previously healthy 25-year-old German man with a cerebellar abscess caused by Fusobacterium nucleatum that resulted in rapid brain death. Toxicological screening showed positivity for amphetamines and cannabis. The diagnosis was obtained by polymerase chain reaction amplification of bacterial deoxyribonucleic acid in cerebrospinal fluid. CONCLUSIONS: In drug users clinicians should think about rare causes of brain abscesses/meningitis. Early diagnosis is necessary and justifies the use of molecular techniques.
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spelling pubmed-40628962014-06-20 Rapid brain death caused by a cerebellar abscess with Fusobacterium nucleatum in a young man with drug abuse: a case report Hischebeth, Gunnar TR Keil, Vera C Gentil, Katrin Boström, Azize Kuchelmeister, Klaus Bekeredjian-Ding, Isabelle BMC Res Notes Case Report BACKGROUND: Fusobacterium nucleatum is a strict anaerobic microorganism that causes disease entities such as periodontal and soft tissue abscesses, pulmonary and intraabdominal infections and very rarely intracerebral infections. CASE PRESENTATION: Here, we report the rare case of a previously healthy 25-year-old German man with a cerebellar abscess caused by Fusobacterium nucleatum that resulted in rapid brain death. Toxicological screening showed positivity for amphetamines and cannabis. The diagnosis was obtained by polymerase chain reaction amplification of bacterial deoxyribonucleic acid in cerebrospinal fluid. CONCLUSIONS: In drug users clinicians should think about rare causes of brain abscesses/meningitis. Early diagnosis is necessary and justifies the use of molecular techniques. BioMed Central 2014-06-10 /pmc/articles/PMC4062896/ /pubmed/24915846 http://dx.doi.org/10.1186/1756-0500-7-353 Text en Copyright © 2014 Hischebeth et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Hischebeth, Gunnar TR
Keil, Vera C
Gentil, Katrin
Boström, Azize
Kuchelmeister, Klaus
Bekeredjian-Ding, Isabelle
Rapid brain death caused by a cerebellar abscess with Fusobacterium nucleatum in a young man with drug abuse: a case report
title Rapid brain death caused by a cerebellar abscess with Fusobacterium nucleatum in a young man with drug abuse: a case report
title_full Rapid brain death caused by a cerebellar abscess with Fusobacterium nucleatum in a young man with drug abuse: a case report
title_fullStr Rapid brain death caused by a cerebellar abscess with Fusobacterium nucleatum in a young man with drug abuse: a case report
title_full_unstemmed Rapid brain death caused by a cerebellar abscess with Fusobacterium nucleatum in a young man with drug abuse: a case report
title_short Rapid brain death caused by a cerebellar abscess with Fusobacterium nucleatum in a young man with drug abuse: a case report
title_sort rapid brain death caused by a cerebellar abscess with fusobacterium nucleatum in a young man with drug abuse: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062896/
https://www.ncbi.nlm.nih.gov/pubmed/24915846
http://dx.doi.org/10.1186/1756-0500-7-353
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