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Aberrant PTPRO methylation in tumor tissues as a potential biomarker that predicts clinical outcomes in breast cancer patients

BACKGROUND: Aberrant hypermethylation of gene promoter regions is a primary mechanism by which tumor suppressor genes become inactivated in breast cancer. Epigenetic inactivation of the protein tyrosine phosphatase receptor-type O gene (PTPRO) has been described in several types of cancer. RESULTS:...

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Detalles Bibliográficos
Autores principales: Li, Shao-ying, Li, Rong, Chen, Yu-li, Xiong, Li-kuang, Wang, Hui-lin, Rong, Lei, Luo, Rong-cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062905/
https://www.ncbi.nlm.nih.gov/pubmed/24919593
http://dx.doi.org/10.1186/1471-2156-15-67