Cargando…
Androgen Receptor Activation in Castration-Recurrent Prostate Cancer: The Role of Src-Family and Ack1 Tyrosine Kinases
There is growing appreciation that castration-recurrent prostate cancer (CR-CaP) is driven by the continued expression of androgen receptor (AR). AR activation in CR-CaP through various mechanisms, including AR overexpression, expression of AR splice variants or mutants, increased expression of co-r...
Autor principal: | Gelman, Irwin H. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062955/ https://www.ncbi.nlm.nih.gov/pubmed/24948875 http://dx.doi.org/10.7150/ijbs.8264 |
Ejemplares similares
-
Dasatinib inhibits site-specific tyrosine phosphorylation of androgen receptor by Ack1 and Src kinases
por: Liu, Yuanbo, et al.
Publicado: (2010) -
Src promotes castration-recurrent prostate cancer through androgen receptor-dependent canonical and non-canonical transcriptional signatures
por: Chattopadhyay, Indranil, et al.
Publicado: (2016) -
Interaction between androgen receptor and coregulator SLIRP is regulated by Ack1 tyrosine kinase and androgen
por: De Silva, Dinuka, et al.
Publicado: (2019) -
Regulation of Ack-Family Nonreceptor Tyrosine Kinases
por: Prieto-Echagüe, Victoria, et al.
Publicado: (2011) -
Src controls castration recurrence of CWR22 prostate cancer xenografts
por: Su, Bing, et al.
Publicado: (2013)