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Synergistic antitumor effects of a TGFβ inhibitor and cyclophosphamide
In a mouse model of breast carcinoma, the combination of cyclophosphamide and transforming growth factor β1,2,3 (TGFβ1,2,3)-targeting antibody achieved superior antineoplastic effects. This novel paradigm of synergistic chemoimmunotherapy promises to improve the clinical outcome of cancer patients w...
Autores principales: | Chen, Xin, Wakefield, Lalage M, Oppenheim, Joost J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063140/ https://www.ncbi.nlm.nih.gov/pubmed/25050195 http://dx.doi.org/10.4161/onci.28247 |
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