Cargando…

The role of CUX1 in antagonizing NF-κB signaling in TAMs

Macrophages represent a major component of the tumor microenvironment and contribute to neoplasia initiation and cancer progression. However, the molecular mechanisms underlying these phenomena are only partially understood. Manipulating the transcriptional activity of the macrophage functional spec...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kühnemuth, Benjamin, Michl, Patrick
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Landes Bioscience 2014
Materias:	Author's View
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063149/ https://www.ncbi.nlm.nih.gov/pubmed/25050198 http://dx.doi.org/10.4161/onci.28270

Ejemplares similares

A new role for NFκB in immunosurveillance and its implications for cancer immunotherapy
por: Beg, Amer A, et al.
Publicado: (2013)

TAM macrophages promote growth and metastasis within the cancer ecosystem
por: Zarif, Jelani C, et al.
Publicado: (2014)

HSP90 inhibitor antagonizing MIF: The specifics of pleiotropic cancer drug candidates
por: Schulz, Ramona, et al.
Publicado: (2012)

Antagonizing the innate pattern recognition receptor CD204 to improve dendritic cell-targeted cancer immunotherapy
por: Yu, Xiaofei, et al.
Publicado: (2012)

PTP1B: mediating ROS signaling to silence genes
por: Boivin, Benoit, et al.
Publicado: (2015)

Lysosomotropic REV-ERB antagonism: A metabolic connection between circadian rhythm and autophagy may tell cancer cells “it's time to die”
por: Grimaldi, Benedetto
Publicado: (2014)

ROS signaling during granzyme B-mediated apoptosis
por: Martinvalet, Denis
Publicado: (2015)

Desmoplastic melanoma: C>Ts and NF‐κB
por: Rabbie, Roy, et al.
Publicado: (2016)

Forging a link between oncogenic signaling and immunosuppression in melanoma
por: Khalili, Jahan S., et al.
Publicado: (2013)

CUX1—Transcriptional Master Regulator of Tumor Progression in Pancreatic Neuroendocrine Tumors
por: Krug, Sebastian, et al.
Publicado: (2020)

Senescence and NFκB: A trojan horse in tumors?
por: Crescenzi, Elvira, et al.
Publicado: (2012)

VEGF signaling, mTOR complexes, and the endoplasmic reticulum: Towards a role of metabolic sensing in the regulation of angiogenesis
por: Karali, Evdoxia, et al.
Publicado: (2014)

An expanded role for mTORC1 in autophagy
por: Kim, Young-Mi, et al.
Publicado: (2015)

The metabolic reprogramming and vulnerability of SF3B1 mutations
por: Dalton, W. Brian
Publicado: (2020)

A novel role for TTK in homologous recombination: implications for breast cancer radiosensitivity
por: Chandler, Benjamin C., et al.
Publicado: (2020)

New insights on the role of CD8(+)CD57(+) T-cells in cancer
por: Wu, Richard C., et al.
Publicado: (2012)

Anti-PD-1 antibodies for the treatment of B-cell lymphoma: Importance of PD-1(+) T-cell subsets
por: Chu, Fuliang, et al.
Publicado: (2014)

The PHD motif of Map3k1 activates cytokine-dependent MAPK signaling
por: Gallagher, Ewen, et al.
Publicado: (2015)

CX3CL1 at the crossroad of EGF signals: Relevance for the progression of ERBB2(+) breast carcinoma
por: Tardáguila, Manuel, et al.
Publicado: (2013)

Unconventional role of RAC1 in MET-driven anchorage-independent tumor growth
por: Hervieu, Alexia, et al.
Publicado: (2020)

Early detection of the aflatoxin B(1) mutational fingerprint: A diagnostic tool for liver cancer
por: Fedeles, Bogdan I., et al.
Publicado: (2017)

Dual role of PRMT1-dependent arginine methylation in cellular responses to genotoxic stress
por: Giambruno, Roberto, et al.
Publicado: (2020)

Continuous 4–1BB co-stimulatory signals for the optimal expansion of tumor-infiltrating lymphocytes for adoptive T-cell therapy
por: Chacon, Jessica Ann, et al.
Publicado: (2013)

Another string to the polo bow: a new mitotic role of PLK1 in centromere protection
por: Olukoga, Tomisin, et al.
Publicado: (2019)

MAPK signaling regulates the efficacy of chemoimmunotherapy
por: Ghiringhelli, François
Publicado: (2022)

Lenalidomide induces degradation of IKZF1 and IKZF3
por: Krönke, Jan, et al.
Publicado: (2014)

Topical phenylbutyrate antagonizes NF-κB signaling and resolves corneal inflammation
por: Koganti, Raghuram, et al.
Publicado: (2022)

The ELR(+)CXCL chemokines and their receptors CXCR1/CXCR2: A signaling axis and new target for the treatment of renal cell carcinoma
por: Giuliano, Sandy, et al.
Publicado: (2014)

A cancerous web: signaling, metabolism, and the epigenome
por: Lee, Joyce V., et al.
Publicado: (2014)

CUX1 Enhances Pancreatic Cancer Formation by Synergizing with KRAS and Inducing MEK/ERK-Dependent Proliferation
por: Griesmann, Heidi, et al.
Publicado: (2021)

Rage mediated DAMP signaling in intestinal tumorigenesis
por: Heijmans, Jarom, et al.
Publicado: (2012)

Modulating CD27 signaling to treat cancer
por: Riether, Carsten, et al.
Publicado: (2012)

Dynamic ERK signaling regulation in intestinal tumorigenesis
por: Muta, Yu, et al.
Publicado: (2018)

Blockade of the PD-1 pathway enhances the efficacy of adoptive cell therapy against cancer
por: Peng, Weiyi, et al.
Publicado: (2013)

Controlling the mitochondrial antisense – role of the SUV3-PNPase complex and its co-factor GRSF1 in mitochondrial RNA surveillance
por: Pietras, Zbigniew, et al.
Publicado: (2018)

T cell immunosurveillance controls B lymphoma development
por: Kallies, Axel
Publicado: (2014)

SIN3B, the SASP, and pancreatic cancer
por: Cantor, David J, et al.
Publicado: (2014)

Dendritic cell-based vaccines: Shining the spotlight on signal 3
por: Linette, Gerald P, et al.
Publicado: (2013)

CD44 regulates Wnt signaling at the level of LRP6
por: Orian-Rousseau, Véronique, et al.
Publicado: (2015)

Inhibition of RANK signaling as a potential immunotherapy in breast cancer
por: Gómez-Aleza, C, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_vugds8tr3c05p47g1lg3rr82qp