Immune response markers in sentinel nodes may predict melanoma progression

We recently reported that variable expression of immune-response genes distinguishes tumor positive sentinel nodes in melanoma patients with malignant progression from those with non-progressing disease. Our results depict sentinel nodes as sites in which immune functions are associated with metasta...

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Detalles Bibliográficos
Autores principales: Rodolfo, Monica, Castelli, Chiara, Rivoltini, Licia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063153/
https://www.ncbi.nlm.nih.gov/pubmed/25050216
http://dx.doi.org/10.4161/onci.28498
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author Rodolfo, Monica
Castelli, Chiara
Rivoltini, Licia
author_facet Rodolfo, Monica
Castelli, Chiara
Rivoltini, Licia
author_sort Rodolfo, Monica
collection PubMed
description We recently reported that variable expression of immune-response genes distinguishes tumor positive sentinel nodes in melanoma patients with malignant progression from those with non-progressing disease. Our results depict sentinel nodes as sites in which immune functions are associated with metastatic disease and identify CD30 as a host immune-related cancer prognostic marker and potential therapeutic target.
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spelling pubmed-40631532014-07-21 Immune response markers in sentinel nodes may predict melanoma progression Rodolfo, Monica Castelli, Chiara Rivoltini, Licia Oncoimmunology Author's View We recently reported that variable expression of immune-response genes distinguishes tumor positive sentinel nodes in melanoma patients with malignant progression from those with non-progressing disease. Our results depict sentinel nodes as sites in which immune functions are associated with metastatic disease and identify CD30 as a host immune-related cancer prognostic marker and potential therapeutic target. Landes Bioscience 2014-04-15 /pmc/articles/PMC4063153/ /pubmed/25050216 http://dx.doi.org/10.4161/onci.28498 Text en Copyright © 2014 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Rodolfo, Monica
Castelli, Chiara
Rivoltini, Licia
Immune response markers in sentinel nodes may predict melanoma progression
title Immune response markers in sentinel nodes may predict melanoma progression
title_full Immune response markers in sentinel nodes may predict melanoma progression
title_fullStr Immune response markers in sentinel nodes may predict melanoma progression
title_full_unstemmed Immune response markers in sentinel nodes may predict melanoma progression
title_short Immune response markers in sentinel nodes may predict melanoma progression
title_sort immune response markers in sentinel nodes may predict melanoma progression
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063153/
https://www.ncbi.nlm.nih.gov/pubmed/25050216
http://dx.doi.org/10.4161/onci.28498
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AT rivoltinilicia immuneresponsemarkersinsentinelnodesmaypredictmelanomaprogression

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