Cargando…
The ELR(+)CXCL chemokines and their receptors CXCR1/CXCR2: A signaling axis and new target for the treatment of renal cell carcinoma
The long-term efficacy of anti-angiogenesis drugs targeting vascular endothelial growth factor (VEGF) and VEGF receptors in the treatment of renal cell carcinoma (RCC) has been lacking. We have shown that the ELR(+)CXCL cytokines and their (C-X-C) chemokine receptors, namely CXCR1 and CXCR2, stimula...
Autores principales: | Giuliano, Sandy, Guyot, Mélanie, Grépin, Renaud, Pagès, Gilles |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063157/ https://www.ncbi.nlm.nih.gov/pubmed/25050209 http://dx.doi.org/10.4161/onci.28399 |
Ejemplares similares
-
Targeting of the ELR+CXCL/CXCR1/2 Pathway Is a Relevant Strategy for the Treatment of Paediatric Medulloblastomas
por: Penco-Campillo, Manon, et al.
Publicado: (2022) -
The Role of the CXCL12/CXCR4/CXCR7 Chemokine Axis in Cancer
por: Shi, Yi, et al.
Publicado: (2020) -
The CXCL12/CXCR4 chemokine ligand/receptor axis in cardiovascular disease
por: Döring, Yvonne, et al.
Publicado: (2014) -
Inhibition of CXCLs/CXCR2 axis in the tumor microenvironment might be a potent therapeutics for pancreatic cancer
por: Ijichi, Hideaki
Publicado: (2012) -
Chemokines and chemokine receptors required for optimal responses to anticancer chemotherapy
por: Ma, Yuting, et al.
Publicado: (2014)