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Modulation of TonEBP activity by SUMO modification in response to hypertonicity

TonEBP is a DNA binding transcriptional enhancer that enables cellular adaptation to hypertonic stress by promoting expression of specific genes. TonEBP expression is very high in the renal medulla because local hypertonicity stimulates its expression. Given the high level of expression, it is not w...

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Detalles Bibliográficos
Autores principales: Kim, Jeong-Ah, Kwon, Mi Jin, Lee-Kwon, Whaseon, Choi, Soo Youn, Sanada, Satoru, Kwon, Hyug Moo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063170/
https://www.ncbi.nlm.nih.gov/pubmed/24994984
http://dx.doi.org/10.3389/fphys.2014.00200