Cargando…

Modulation of TonEBP activity by SUMO modification in response to hypertonicity

TonEBP is a DNA binding transcriptional enhancer that enables cellular adaptation to hypertonic stress by promoting expression of specific genes. TonEBP expression is very high in the renal medulla because local hypertonicity stimulates its expression. Given the high level of expression, it is not w...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Jeong-Ah, Kwon, Mi Jin, Lee-Kwon, Whaseon, Choi, Soo Youn, Sanada, Satoru, Kwon, Hyug Moo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2014
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063170/ https://www.ncbi.nlm.nih.gov/pubmed/24994984 http://dx.doi.org/10.3389/fphys.2014.00200

Ejemplares similares

Transcriptional Regulator TonEBP Mediates Oxidative Damages in Ischemic Kidney Injury
por: Yoo, Eun Jin, et al.
Publicado: (2019)

TonEBP suppresses IL-10-mediated immunomodulation
por: Choi, Soo Youn, et al.
Publicado: (2016)

TonEBP suppresses adipogenesis and insulin sensitivity by blocking epigenetic transition of PPARγ2
por: Ho Lee, Jun, et al.
Publicado: (2015)

TonEBP Promotes β-Cell Survival under ER Stress by Enhancing Autophagy
por: Kang, Hyun Je, et al.
Publicado: (2020)

TonEBP and SMIT expression in human placenta
por: Shin, Jung-A, et al.
Publicado: (2012)

LPS-induced NFκB enhanceosome requires TonEBP/NFAT5 without DNA binding
por: Lee, Hwan Hee, et al.
Publicado: (2016)

Microglial TonEBP mediates LPS-induced inflammation and memory loss as transcriptional cofactor for NF-κB and AP-1
por: Jeong, Gyu Won, et al.
Publicado: (2020)

TonEBP Suppresses the HO-1 Gene by Blocking Recruitment of Nrf2 to Its Promoter
por: Yoo, Eun Jin, et al.
Publicado: (2019)

TonEBP in dendritic cells mediates pro-inflammatory maturation and Th1/Th17 responses
por: Ye, Byeong Jin, et al.
Publicado: (2020)

TonEBP in Myeloid Cells Promotes Obesity-Induced Insulin Resistance and Inflammation Through Adipose Tissue Remodeling
por: Lee, Hwan Hee, et al.
Publicado: (2022)

TonEBP Regulates PCNA Polyubiquitination in Response to DNA Damage through Interaction with SHPRH and USP1
por: Kang, Hyun Je, et al.
Publicado: (2019)

TonEBP/NFAT5 promotes obesity and insulin resistance by epigenetic suppression of white adipose tissue beiging
por: Lee, Hwan Hee, et al.
Publicado: (2019)

TonEBP recognizes R-loops and initiates m6A RNA methylation for R-loop resolution
por: Kang, Hyun Je, et al.
Publicado: (2020)

Focal adhesion kinase regulates the activity of the osmosensitive transcription factor TonEBP/NFAT5 under hypertonic conditions
por: Neuhofer, Wolfgang, et al.
Publicado: (2014)

Osmoprotective Transcription Factor NFAT5/TonEBP Modulates Nuclear Factor-κB Activity
por: Roth, Isabelle, et al.
Publicado: (2010)

TonEBP/NFAT5 regulates ACTBL2 expression in biomechanically activated vascular smooth muscle cells
por: Hödebeck, Maren, et al.
Publicado: (2014)

TonEBP/NFAT5 haploinsufficiency attenuates hippocampal inflammation in high-fat diet/streptozotocin-induced diabetic mice
por: Lee, Jong Youl, et al.
Publicado: (2017)

Transcription Factor TonEBP Stimulates Hyperosmolality-Dependent Arginine Vasopressin Gene Expression in the Mouse Hypothalamus
por: Kim, Dong Hee, et al.
Publicado: (2021)

TonEBP modulates the protective effect of taurine in ischemia-induced cytotoxicity in cardiomyocytes
por: Yang, Y J, et al.
Publicado: (2015)

TonEBP regulates the hyperosmotic expression of aquaporin 1 and 5 in the intervertebral disc
por: Snuggs, J. W., et al.
Publicado: (2021)

Lack of evidence for involvement of TonEBP and hyperosmotic stimulus in induction of autophagy in the nucleus pulposus
por: Liu, Chao, et al.
Publicado: (2017)

TonEBP suppresses adipocyte differentiation via modulation of early signaling in 3T3-L1 cells
por: Kim, Soo Jin, et al.
Publicado: (2016)

The TLR-2/TonEBP signaling pathway regulates 29-kDa fibronectin fragment-dependent expression of matrix metalloproteinases
por: Hwang, Hyun Sook, et al.
Publicado: (2021)

Extracellular osmolarity regulates matrix homeostasis in the intervertebral disc and articular cartilage: Evolving role of TonEBP
por: Johnson, Zariel I., et al.
Publicado: (2014)

TonEBP Haploinsufficiency Attenuates Microglial Activation and Memory Deficits in Middle-Aged and Amyloid β Oligomer-Treated Mice
por: Lee, Jong Youl, et al.
Publicado: (2023)

Involvement of TonEBP/NFAT5 in osmoadaptative response of human retinal pigmented epithelial cells to hyperosmolar stress
por: Libert, Sarah, et al.
Publicado: (2016)

Nucleus pulposus primary cilia alter their length in response to changes in extracellular osmolarity but do not control TonEBP-mediated osmoregulation
por: Choi, Hyowon, et al.
Publicado: (2019)

Genistein‐Calcitriol Mitigates Hyperosmotic Stress‐Induced TonEBP, CFTR Dysfunction, VDR Degradation and Inflammation in Dry Eye Disease
por: Panigrahi, Trailokyanath, et al.
Publicado: (2020)

Osmolyte regulation by TonEBP/NFAT5 during anoxia-recovery and dehydration–rehydration stresses in the freeze-tolerant wood frog (Rana sylvatica)
por: Al-attar, Rasha, et al.
Publicado: (2017)

Mediator of DNA Damage Checkpoint 1 (MDC1) Contributes to High NaCl-Induced Activation of the Osmoprotective Transcription Factor TonEBP/OREBP
por: Kunin, Margarita, et al.
Publicado: (2010)

NFAT5/TonEBP Limits Pulmonary Vascular Resistance in the Hypoxic Lung by Controlling Mitochondrial Reactive Oxygen Species Generation in Arterial Smooth Muscle Cells
por: Laban, Hebatullah, et al.
Publicado: (2021)

High NaCl–induced activation of CDK5 increases phosphorylation of the osmoprotective transcription factor TonEBP/OREBP at threonine 135, which contributes to its rapid nuclear localization
por: Gallazzini, Morgan, et al.
Publicado: (2011)

Functional roles of C/EBPα and SUMO-modification in lung development
por: Chen, Yuan-Dong, et al.
Publicado: (2017)

BMP-2 and TGF-β Stimulate Expression of β1,3-Glucuronosyl Transferase 1 (GlcAT-1) in Nucleus Pulposus Cells Through AP1, TonEBP, and Sp1: Role of MAPKs
por: Hiyama, Akihiko, et al.
Publicado: (2010)

The Role of TonB Gene in Edwardsiella ictaluri Virulence
por: Abdelhamed, Hossam, et al.
Publicado: (2017)

Tonicity-responsive enhancer-binding protein promotes stemness of liver cancer and cisplatin resistance
por: Lee, Jun Ho, et al.
Publicado: (2020)

Inverse Regulation of Lipocalin-2/24p3 Receptor/SLC22A17 and Lipocalin-2 Expression by Tonicity, NFAT5/TonEBP and Arginine Vasopressin in Mouse Cortical Collecting Duct Cells mCCD(cl.1): Implications for Osmotolerance
por: Probst, Stephanie, et al.
Publicado: (2019)

SUMO modification in apoptosis
por: Li, Peiyao, et al.
Publicado: (2020)

Expression, Localization of SUMO-1, and Analyses of Potential SUMOylated Proteins in Bubalus bubalis Spermatozoa
por: Brohi, Rahim Dad, et al.
Publicado: (2017)

The Critical Roles of the SUMO-Specific Protease SENP3 in Human Diseases and Clinical Implications
por: Long, Xiaojun, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_cepeo4el3uq70megj911m7rc9o