A Zinc Linchpin Motif in the MUTYH Glycosylase Interdomain Connector Is Required for Efficient Repair of DNA Damage

[Image: see text] Mammalian MutY glycosylases have a unique architecture that features an interdomain connector (IDC) that joins the catalytic N-terminal domain and 8-oxoguanine (OG) recognition C-terminal domain. The IDC has been shown to be a hub for interactions with protein partners involved in...

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Detalles Bibliográficos
Autores principales: Engstrom, Lisa M., Brinkmeyer, Megan K., Ha, Yang, Raetz, Alan G., Hedman, Britt, Hodgson, Keith O., Solomon, Edward I., David, Sheila S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063174/
https://www.ncbi.nlm.nih.gov/pubmed/24841533
http://dx.doi.org/10.1021/ja502942d

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