Cargando…
Insights into the Binding of Pyridines to the Iron–Sulfur Enzyme IspH
[Image: see text] (E)-1-Hydroxy-2-methylbut-2-enyl 4-diphosphate reductase (IspH) is a [Fe(4)S(4)] cluster-containing enzyme involved in isoprenoid biosynthesis in many bacteria as well as in malaria parasites and is an important drug target. Several inhibitors including amino and thiol substrate an...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2014
|
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063180/ https://www.ncbi.nlm.nih.gov/pubmed/24813236 http://dx.doi.org/10.1021/ja501127j |