Cargando…

Upregulation of the miR-17-92 cluster and its two paraloga in osteosarcoma – reasons and consequences

Osteosarcomas (OS) are aggressive bone tumors characterized by complex karyotypes with highly variable structural and numerical chromosomal aberrations. Although several genes and pathways commonly altered in malignant tumors have also been identified in OS, the molecular pathogenesis and driving ge...

Descripción completa

Detalles Bibliográficos
Autores principales:	Arabi, Leila, Gsponer, Joël R, Smida, Jan, Nathrath, Michaela, Perrina, Valeria, Jundt, Gernot, Ruiz, Christian, Quagliata, Luca, Baumhoer, Daniel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2014
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063253/ https://www.ncbi.nlm.nih.gov/pubmed/24955218

Ejemplares similares

CRIP1 expression is correlated with a favorable outcome and less metastases in osteosarcoma patients
por: Baumhoer, Daniel, et al.
Publicado: (2011)

Structuring osteosarcoma knowledge: an osteosarcoma-gene association database based on literature mining and manual annotation
por: Poos, Kathrin, et al.
Publicado: (2014)

How MicroRNA and Transcription Factor Co-regulatory Networks Affect Osteosarcoma Cell Proliferation
por: Poos, Kathrin, et al.
Publicado: (2013)

Genomic Heterogeneity of Osteosarcoma - Shift from Single Candidates to Functional Modules
por: Poos, Kathrin, et al.
Publicado: (2015)

New Small Molecules Targeting Apoptosis and Cell Viability in Osteosarcoma
por: Maugg, Doris, et al.
Publicado: (2015)

The long non-coding RNA PARTICLE is associated with WWOX and the absence of FRA16D breakage in osteosarcoma patients
por: O'Leary, Valerie Bríd, et al.
Publicado: (2017)

Osteosarcoma cells with genetic signatures of BRCAness are susceptible to the PARP inhibitor talazoparib alone or in combination with chemotherapeutics
por: Engert, Florian, et al.
Publicado: (2016)

TP53 intron 1 hotspot rearrangements are specific to sporadic osteosarcoma and can cause Li-Fraumeni syndrome
por: Ribi, Sebastian, et al.
Publicado: (2015)

Exome sequencing of osteosarcoma reveals mutation signatures reminiscent of BRCA deficiency
por: Kovac, Michal, et al.
Publicado: (2015)

Overactivation of the IGF signalling pathway in osteosarcoma: a potential therapeutic target?
por: Ameline, Baptiste, et al.
Publicado: (2020)

NTRK fusions in osteosarcoma are rare and non‐functional events
por: Ameline, Baptiste, et al.
Publicado: (2020)

DNA methylation-based classifier and gene expression signatures detect BRCAness in osteosarcoma
por: Barenboim, Maxim, et al.
Publicado: (2021)

Solitary pulmonary metastases at first recurrence of osteosarcoma: Presentation, treatment, and survival of 219 patients of the Cooperative Osteosarcoma Study Group
por: Mettmann, Vanessa L., et al.
Publicado: (2023)

The early evolutionary landscape of osteosarcoma provides clues for targeted treatment strategies
por: Kovac, Michal, et al.
Publicado: (2021)

EXM 92-17 03/09/92
por: Daems, G
Publicado: (1992)

LIN92#17
Publicado: (1993)

Secondary Radiation-Induced Bone Tumours Demonstrate a High Degree of Genomic Instability Predictive of a Poor Prognosis
por: Rümenapp, Christine, et al.
Publicado: (2012)

The miR-17-92 cluster/QKI2/β-catenin axis promotes osteosarcoma progression
por: Yang, Hongbo, et al.
Publicado: (2018)

TMAO Upregulates Members of the miR-17/92 Cluster and Impacts Targets Associated with Atherosclerosis
por: Díez-Ricote, Laura, et al.
Publicado: (2022)

Upregulation of miR-17-92 cluster is associated with progression and lymph node metastasis in oesophageal adenocarcinoma
por: Plum, Patrick Sven, et al.
Publicado: (2019)

False-belief reasoning from 3 to 92 years of age
por: Bernstein, Daniel M., et al.
Publicado: (2017)

Allelic Imbalances in Radiation—Associated Acute Myeloid Leukemia
por: Klymenko, Sergiy V., et al.
Publicado: (2011)

MicroRNA Profiling of Salivary Adenoid Cystic Carcinoma: Association of miR-17-92 Upregulation with Poor Outcome
por: Mitani, Yoshitsugu, et al.
Publicado: (2013)

Role of the miR-17∼92 cluster family in cerebellar and medulloblastoma development
por: Zindy, Frederique, et al.
Publicado: (2014)

Minutes from progress meeting, rule based reasoning, 22/5-92
por: Fuchs, J., et al.
Publicado: (1992)

Histone deacetylase inhibitor SAHA epigenetically regulates miR-17-92 cluster and MCM7 to upregulate MICA expression in hepatoma
por: Yang, H, et al.
Publicado: (2015)

P02-014 - Consequences of Arginine 92 mutations in TNFR1
por: Jéru, I, et al.
Publicado: (2013)

Bias in human reasoning: causes and consequences
por: Evans, Jonathan
Publicado: (1989)

Tracking reason: proof, consequence, and truth
por: Azzouni, Jody
Publicado: (2006)

Failure in Asthma Control: Reasons and Consequences
por: Braido, Fulvio
Publicado: (2013)

Minutes of the photon reconstruction meeting held on 17 6 92
por: Goy, C
Publicado: (1992)

Minutes of the searches group meeting held on 17 2 92
por: Medcalf, T
Publicado: (1992)

A complex pattern of chemokine receptor expression is seen in osteosarcoma
por: von Luettichau, Irene, et al.
Publicado: (2008)

Report from the 4th European Bone Sarcoma Networking meeting: focus on osteosarcoma
por: Strauss, Sandra J., et al.
Publicado: (2018)

Pseudocystic Osteosarcoma: A Potential Diagnostic Pitfall - Case Report
por: Abcha, Oussama, et al.
Publicado: (2021)

A Rb1 promoter variant with reduced activity contributes to osteosarcoma susceptibility in irradiated mice
por: Rosemann, Michael, et al.
Publicado: (2014)

S92. REASONS TO START SMOKING CANNABIS: A CASE CONTROL-ANALYSIS FROM THE EUGEI STUDY
por: Spinazzola, Edoardo, et al.
Publicado: (2020)

Minutes of the QCD / Inclusive particle production meeting: 17 12 92
por: ten Have, I
Publicado: (1992)

Feud or Friend? The Role of the miR-17-92 Cluster in Tumorigenesis
por: Xiang, Jie, et al.
Publicado: (2010)

miR-17–92 cluster: ups and downs in cancer and aging
por: Grillari, Johannes, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_si7u5pvbs2stfhg8n3imrketue