Structure–Activity Relationships of Quinoxaline-Based 5-HT(3)A and 5-HT(3)AB Receptor-Selective Ligands

Until recently, discriminating between homomeric 5-HT(3)A and heteromeric 5-HT(3)AB receptors was only possible with ligands that bind in the receptor pore. This study describes the first series of ligands that can discriminate between these receptor types at the level of the orthosteric binding sit...

Descripción completa

Detalles Bibliográficos
Autores principales: Thompson, Andrew J, Verheij, Mark H P, van Muijlwijk-Koezen, Jacqueline E, Lummis, Sarah C R, Leurs, Rob, de Esch, Iwan J P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2013
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063337/
https://www.ncbi.nlm.nih.gov/pubmed/23640722
http://dx.doi.org/10.1002/cmdc.201300032

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063337/
https://www.ncbi.nlm.nih.gov/pubmed/23640722
http://dx.doi.org/10.1002/cmdc.201300032

Ejemplares similares