Cargando…

A novel melting curve-based method for detecting c-kit mutations in acute myeloid leukemia

The c-kit gene encodes a class III tyrosine kinase receptor. Specific somatic mutations in c-kit have been associated with acute myeloid leukemia (AML) and are markers of a poor prognosis in AML. Various methods have been used to detect the c-kit gene mutation; however, the suitability of these meth...

Descripción completa

Detalles Bibliográficos
Autores principales: LU, QUANYI, HUANG, XIAO, CHEN, HUAYING, ZHAO, XIAOMIN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063585/
https://www.ncbi.nlm.nih.gov/pubmed/24959227
http://dx.doi.org/10.3892/ol.2014.2128