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A novel melting curve-based method for detecting c-kit mutations in acute myeloid leukemia

The c-kit gene encodes a class III tyrosine kinase receptor. Specific somatic mutations in c-kit have been associated with acute myeloid leukemia (AML) and are markers of a poor prognosis in AML. Various methods have been used to detect the c-kit gene mutation; however, the suitability of these meth...

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Detalles Bibliográficos
Autores principales:	LU, QUANYI, HUANG, XIAO, CHEN, HUAYING, ZHAO, XIAOMIN
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2014
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063585/ https://www.ncbi.nlm.nih.gov/pubmed/24959227 http://dx.doi.org/10.3892/ol.2014.2128

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