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P130cas is required for TGF-β1-mediated epithelial-mesenchymal transition in lung cancer

In lung cancer A549 cells, the present study evaluated the associations between p130cas expression and the activation of p38 or Smad2, which are components of two of the main signaling pathways of transforming growth factor-β1 (TGF-β1), i.e., epithelial-mesenchymal transition (EMT) and apoptosis, re...

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Detalles Bibliográficos
Autores principales: DENG, BO, TAN, QUN-YOU, WANG, RU-WEN, JIANG, YAO-GUANG, ZHOU, JING-HAI, HUANG, WEI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063590/
https://www.ncbi.nlm.nih.gov/pubmed/24959295
http://dx.doi.org/10.3892/ol.2014.2123