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Obstructive jaundice due to von Hippel-Lindau disease-associated pancreatic lesions: A case report
von Hippel-Lindau (VHL) disease is an autosomal dominantly inherited neoplastic syndrome that may lead to pancreatic masses and obstructive jaundice. The present study describes the case of a 20-year-old male who suffered from obstructive jaundice due to VHL disease-associated pancreatic lesions who...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063595/ https://www.ncbi.nlm.nih.gov/pubmed/24959293 http://dx.doi.org/10.3892/ol.2014.2098 |
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author | LIANG, XIAOYU HU, FANGUO MA, ZHICHENG LI, NAN CHEN, YAN ZHANG, JIE |
author_facet | LIANG, XIAOYU HU, FANGUO MA, ZHICHENG LI, NAN CHEN, YAN ZHANG, JIE |
author_sort | LIANG, XIAOYU |
collection | PubMed |
description | von Hippel-Lindau (VHL) disease is an autosomal dominantly inherited neoplastic syndrome that may lead to pancreatic masses and obstructive jaundice. The present study describes the case of a 20-year-old male who suffered from obstructive jaundice due to VHL disease-associated pancreatic lesions whose primary symptom was dizziness, followed by the appearance of jaundice. Since the excision of the renal cell carcinomas was not possible, the patient also refused surgery to resect the pancreatic head mass. A metallic stent was placed at the stenosis site of the common bile duct. Percutaneous transhepatic cholangiography (PTCD) surgery was later performed following complete blockage of the stent, however, to date, the patient continues to rely on PTCD. VHL disease-associated pancreatic lesions are rarely the direct cause of mortality, however, obstructive jaundice due to these lesions may be lethal. Therefore, the treatment of patients with incurable renal or central nervous system tumors and obstructive jaundice presents a problem. |
format | Online Article Text |
id | pubmed-4063595 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | D.A. Spandidos |
record_format | MEDLINE/PubMed |
spelling | pubmed-40635952014-06-23 Obstructive jaundice due to von Hippel-Lindau disease-associated pancreatic lesions: A case report LIANG, XIAOYU HU, FANGUO MA, ZHICHENG LI, NAN CHEN, YAN ZHANG, JIE Oncol Lett Articles von Hippel-Lindau (VHL) disease is an autosomal dominantly inherited neoplastic syndrome that may lead to pancreatic masses and obstructive jaundice. The present study describes the case of a 20-year-old male who suffered from obstructive jaundice due to VHL disease-associated pancreatic lesions whose primary symptom was dizziness, followed by the appearance of jaundice. Since the excision of the renal cell carcinomas was not possible, the patient also refused surgery to resect the pancreatic head mass. A metallic stent was placed at the stenosis site of the common bile duct. Percutaneous transhepatic cholangiography (PTCD) surgery was later performed following complete blockage of the stent, however, to date, the patient continues to rely on PTCD. VHL disease-associated pancreatic lesions are rarely the direct cause of mortality, however, obstructive jaundice due to these lesions may be lethal. Therefore, the treatment of patients with incurable renal or central nervous system tumors and obstructive jaundice presents a problem. D.A. Spandidos 2014-07 2014-04-28 /pmc/articles/PMC4063595/ /pubmed/24959293 http://dx.doi.org/10.3892/ol.2014.2098 Text en Copyright © 2014, Spandidos Publications http://creativecommons.org/licenses/by/3.0 This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited. |
spellingShingle | Articles LIANG, XIAOYU HU, FANGUO MA, ZHICHENG LI, NAN CHEN, YAN ZHANG, JIE Obstructive jaundice due to von Hippel-Lindau disease-associated pancreatic lesions: A case report |
title | Obstructive jaundice due to von Hippel-Lindau disease-associated pancreatic lesions: A case report |
title_full | Obstructive jaundice due to von Hippel-Lindau disease-associated pancreatic lesions: A case report |
title_fullStr | Obstructive jaundice due to von Hippel-Lindau disease-associated pancreatic lesions: A case report |
title_full_unstemmed | Obstructive jaundice due to von Hippel-Lindau disease-associated pancreatic lesions: A case report |
title_short | Obstructive jaundice due to von Hippel-Lindau disease-associated pancreatic lesions: A case report |
title_sort | obstructive jaundice due to von hippel-lindau disease-associated pancreatic lesions: a case report |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063595/ https://www.ncbi.nlm.nih.gov/pubmed/24959293 http://dx.doi.org/10.3892/ol.2014.2098 |
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