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Obstructive jaundice due to von Hippel-Lindau disease-associated pancreatic lesions: A case report

von Hippel-Lindau (VHL) disease is an autosomal dominantly inherited neoplastic syndrome that may lead to pancreatic masses and obstructive jaundice. The present study describes the case of a 20-year-old male who suffered from obstructive jaundice due to VHL disease-associated pancreatic lesions who...

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Autores principales: LIANG, XIAOYU, HU, FANGUO, MA, ZHICHENG, LI, NAN, CHEN, YAN, ZHANG, JIE
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063595/
https://www.ncbi.nlm.nih.gov/pubmed/24959293
http://dx.doi.org/10.3892/ol.2014.2098
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author LIANG, XIAOYU
HU, FANGUO
MA, ZHICHENG
LI, NAN
CHEN, YAN
ZHANG, JIE
author_facet LIANG, XIAOYU
HU, FANGUO
MA, ZHICHENG
LI, NAN
CHEN, YAN
ZHANG, JIE
author_sort LIANG, XIAOYU
collection PubMed
description von Hippel-Lindau (VHL) disease is an autosomal dominantly inherited neoplastic syndrome that may lead to pancreatic masses and obstructive jaundice. The present study describes the case of a 20-year-old male who suffered from obstructive jaundice due to VHL disease-associated pancreatic lesions whose primary symptom was dizziness, followed by the appearance of jaundice. Since the excision of the renal cell carcinomas was not possible, the patient also refused surgery to resect the pancreatic head mass. A metallic stent was placed at the stenosis site of the common bile duct. Percutaneous transhepatic cholangiography (PTCD) surgery was later performed following complete blockage of the stent, however, to date, the patient continues to rely on PTCD. VHL disease-associated pancreatic lesions are rarely the direct cause of mortality, however, obstructive jaundice due to these lesions may be lethal. Therefore, the treatment of patients with incurable renal or central nervous system tumors and obstructive jaundice presents a problem.
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spelling pubmed-40635952014-06-23 Obstructive jaundice due to von Hippel-Lindau disease-associated pancreatic lesions: A case report LIANG, XIAOYU HU, FANGUO MA, ZHICHENG LI, NAN CHEN, YAN ZHANG, JIE Oncol Lett Articles von Hippel-Lindau (VHL) disease is an autosomal dominantly inherited neoplastic syndrome that may lead to pancreatic masses and obstructive jaundice. The present study describes the case of a 20-year-old male who suffered from obstructive jaundice due to VHL disease-associated pancreatic lesions whose primary symptom was dizziness, followed by the appearance of jaundice. Since the excision of the renal cell carcinomas was not possible, the patient also refused surgery to resect the pancreatic head mass. A metallic stent was placed at the stenosis site of the common bile duct. Percutaneous transhepatic cholangiography (PTCD) surgery was later performed following complete blockage of the stent, however, to date, the patient continues to rely on PTCD. VHL disease-associated pancreatic lesions are rarely the direct cause of mortality, however, obstructive jaundice due to these lesions may be lethal. Therefore, the treatment of patients with incurable renal or central nervous system tumors and obstructive jaundice presents a problem. D.A. Spandidos 2014-07 2014-04-28 /pmc/articles/PMC4063595/ /pubmed/24959293 http://dx.doi.org/10.3892/ol.2014.2098 Text en Copyright © 2014, Spandidos Publications http://creativecommons.org/licenses/by/3.0 This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Articles
LIANG, XIAOYU
HU, FANGUO
MA, ZHICHENG
LI, NAN
CHEN, YAN
ZHANG, JIE
Obstructive jaundice due to von Hippel-Lindau disease-associated pancreatic lesions: A case report
title Obstructive jaundice due to von Hippel-Lindau disease-associated pancreatic lesions: A case report
title_full Obstructive jaundice due to von Hippel-Lindau disease-associated pancreatic lesions: A case report
title_fullStr Obstructive jaundice due to von Hippel-Lindau disease-associated pancreatic lesions: A case report
title_full_unstemmed Obstructive jaundice due to von Hippel-Lindau disease-associated pancreatic lesions: A case report
title_short Obstructive jaundice due to von Hippel-Lindau disease-associated pancreatic lesions: A case report
title_sort obstructive jaundice due to von hippel-lindau disease-associated pancreatic lesions: a case report
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063595/
https://www.ncbi.nlm.nih.gov/pubmed/24959293
http://dx.doi.org/10.3892/ol.2014.2098
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