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Leptin inhibits proliferation of breast cancer cells at supraphysiological concentrations by inhibiting mitogen-activated protein kinase signaling

Leptin is a hormone secreted by white fat tissue and signals the amount of overall body fat to the hypothalamus. The circulating concentration of leptin correlates with the level of obesity. Breast cancer risk is higher in obese postmenopausal women compared with postmenopausal women of a normal wei...

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Detalles Bibliográficos
Autores principales: WEICHHAUS, MICHAEL, BROOM, JOHN, WAHLE, KLAUS, BERMANO, GIOVANNA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063604/
https://www.ncbi.nlm.nih.gov/pubmed/24959279
http://dx.doi.org/10.3892/ol.2014.2085

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