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FLT3 Internal Tandem Duplication and D835 Mutations in Patients with Acute Lymphoblastic Leukemia and its Clinical Significance

The fms-like tyrosine kinase 3 (FLT3) gene is a member of the class III receptor tyrosine kinase family. Mutations of FLT3 were first described in 1997 and account for the most frequent molecular mutations in acute myeloid leukemia. Currently, there is no published data on FLT3 mutations in Saudi ac...

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Detalles Bibliográficos
Autores principales: Elyamany, Ghaleb, Awad, Mohammed, Alsuhaibani, Omar, Fadalla, Kamal, Al Sharif, Omer, Al Shahrani, Mohammad, Alabbas, Fahad, Al-Abulaaly, Abdulaziz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Università Cattolica del Sacro Cuore 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063605/
https://www.ncbi.nlm.nih.gov/pubmed/24959335
http://dx.doi.org/10.4084/MJHID.2014.038