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Hypoxia regulates Toll-like receptor-9 expression and invasive function in human brain cancer cells in vitro
Toll-like receptor-9 (TLR9) is a cellular DNA sensor of the innate immune system. TLR9 is widely expressed in a number of tumors, including brain cancer; however, little is known regarding its regulation and involvement in cancer pathophysiology. The present study demonstrated that hypoxia upregulat...
Autores principales: | SANDHOLM, JOUKO, TUOMELA, JOHANNA, KAUPPILA, JOONAS H., HARRIS, KEVIN W., GRAVES, DAVID, SELANDER, KATRI S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063648/ https://www.ncbi.nlm.nih.gov/pubmed/24959259 http://dx.doi.org/10.3892/ol.2014.2095 |
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