Gd(3+) and Calcium Sensitive, Sodium Leak Currents Are Features of Weak Membrane-Glass Seals in Patch Clamp Recordings

The properties of leaky patch currents in whole cell recording of HEK-293T cells were examined as a means to separate these control currents from expressed sodium and calcium leak channel currents from snail NALCN leak channels possessing both sodium (EKEE) and calcium (EEEE) selectivity filters. Le...

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Detalles Bibliográficos
Autores principales: Boone, Adrienne N., Senatore, Adriano, Chemin, Jean, Monteil, Arnaud, Spafford, J. David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063719/
https://www.ncbi.nlm.nih.gov/pubmed/24945283
http://dx.doi.org/10.1371/journal.pone.0098808

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