Cargando…
STAT3 Modulation to Enhance Motor Neuron Differentiation in Human Neural Stem Cells
Spinal cord injury or amyotrophic lateral sclerosis damages spinal motor neurons and forms a glial scar, which prevents neural regeneration. Signal transducer and activator of transcription 3 (STAT3) plays a critical role in astrogliogenesis and scar formation, and thus a fine modulation of STAT3 si...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063761/ https://www.ncbi.nlm.nih.gov/pubmed/24945434 http://dx.doi.org/10.1371/journal.pone.0100405 |