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STAT3 Modulation to Enhance Motor Neuron Differentiation in Human Neural Stem Cells
Spinal cord injury or amyotrophic lateral sclerosis damages spinal motor neurons and forms a glial scar, which prevents neural regeneration. Signal transducer and activator of transcription 3 (STAT3) plays a critical role in astrogliogenesis and scar formation, and thus a fine modulation of STAT3 si...
Autores principales: | Natarajan, Rajalaxmi, Singal, Vinamrata, Benes, Richard, Gao, Junling, Chan, Hoi, Chen, Haijun, Yu, Yongjia, Zhou, Jia, Wu, Ping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063761/ https://www.ncbi.nlm.nih.gov/pubmed/24945434 http://dx.doi.org/10.1371/journal.pone.0100405 |
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