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Aberrant Expression and Distribution of Enzymes of the Urea Cycle and Other Ammonia Metabolizing Pathways in Dogs with Congenital Portosystemic Shunts
The detoxification of ammonia occurs mainly through conversion of ammonia to urea in the liver via the urea cycle and glutamine synthesis. Congenital portosystemic shunts (CPSS) in dogs cause hyperammonemia eventually leading to hepatic encephalopathy. In this study, the gene expression of urea cycl...
Autores principales: | van Straten, Giora, van Steenbeek, Frank G., Grinwis, Guy C. M., Favier, Robert P., Kummeling, Anne, van Gils, Ingrid H., Fieten, Hille, Groot Koerkamp, Marian J. A., Holstege, Frank C. P., Rothuizen, Jan, Spee, Bart |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063766/ https://www.ncbi.nlm.nih.gov/pubmed/24945279 http://dx.doi.org/10.1371/journal.pone.0100077 |
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