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Altered Goblet Cell Differentiation and Surface Mucus Properties in Hirschsprung Disease

Hirschsprung disease-associated enterocolitis (HAEC) leads to significant mortality and morbidity, but its pathogenesis remains unknown. Changes in the colonic epithelium related to goblet cells and the luminal mucus layer have been postulated to play a key role. Here we show that the colonic epithe...

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Detalles Bibliográficos
Autores principales:	Thiagarajah, Jay R., Yildiz, Hasan, Carlson, Taylor, Thomas, Alyssa R., Steiger, Casey, Pieretti, Alberto, Zukerberg, Lawrence R., Carrier, Rebecca L., Goldstein, Allan M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063789/ https://www.ncbi.nlm.nih.gov/pubmed/24945437 http://dx.doi.org/10.1371/journal.pone.0099944

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