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A global profile of gene promoter methylation in treatment-naïve urothelial cancer

The epigenetic alteration of aberrant hypermethylation in the promoter CpG island of a gene is associated with repression of transcription. In neoplastic cells, aberrant hypermethylation is well described as a mechanism of allele inactivation of particular genes with a tumor suppressor function. To...

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Detalles Bibliográficos
Autores principales:	Ibragimova, Ilsiya, Dulaimi, Essel, Slifker, Michael J, Chen, David DY, Uzzo, Robert G, Cairns, Paul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Landes Bioscience 2014
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063835/ https://www.ncbi.nlm.nih.gov/pubmed/24521710 http://dx.doi.org/10.4161/epi.28078

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