Variable maternal methylation overlapping the nc886/vtRNA2-1 locus is locked between hypermethylated repeats and is frequently altered in cancer

Cancer is as much an epigenetic disease as a genetic one; however, the interplay between these two processes is unclear. Recently, it has been shown that a large proportion of DNA methylation variability can be explained by allele-specific methylation (ASM), either at classical imprinted loci or tho...

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Detalles Bibliográficos
Autores principales: Romanelli, Valeria, Nakabayashi, Kazuhiko, Vizoso, Miguel, Moran, Sebastián, Iglesias-Platas, Isabel, Sugahara, Naoko, Simón, Carlos, Hata, Kenichiro, Esteller, Manel, Court, Franck, Monk, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063837/
https://www.ncbi.nlm.nih.gov/pubmed/24589629
http://dx.doi.org/10.4161/epi.28323

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