Cargando…
Vaccination against Clostridium difficile using toxin fragments: Observations and analysis in animal models
Clostridium difficile is a major cause of antibiotic associated diarrhea. Recently, we have shown that effective protection can be mediated in hamsters through the inclusion of specific recombinant fragments from toxin A and B in a systemically delivered vaccine. Interestingly while neutralizing ant...
Autores principales: | Spencer, Janice, Leuzzi, Rosanna, Buckley, Anthony, Irvine, June, Candlish, Denise, Scarselli, Maria, Douce, Gillian R |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063849/ https://www.ncbi.nlm.nih.gov/pubmed/24637800 http://dx.doi.org/10.4161/gmic.27712 |
Ejemplares similares
-
Infection of hamsters with the UK Clostridium
difficile ribotype 027 outbreak strain R20291
por: Buckley, Anthony M., et al.
Publicado: (2011) -
Susceptibility of Hamsters to Clostridium difficile Isolates of Differing Toxinotype
por: Buckley, Anthony M., et al.
Publicado: (2013) -
Bile salt metabolism is not the only factor contributing to Clostridioides (Clostridium) difficile disease severity in the murine model of disease
por: Jukes, Caitlin A., et al.
Publicado: (2019) -
Lighting Up Clostridium Difficile: Reporting Gene Expression Using Fluorescent Lov Domains
por: Buckley, Anthony M., et al.
Publicado: (2016) -
Phase variation of Clostridium difficile virulence factors
por: Anjuwon-Foster, Brandon R., et al.
Publicado: (2017)