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Cell Cycle Modulation by Marek’s Disease Virus: The Tegument Protein VP22 Triggers S-Phase Arrest and DNA Damage in Proliferating Cells

Marek’s disease is one of the most common viral diseases of poultry affecting chicken flocks worldwide. The disease is caused by an alphaherpesvirus, the Marek’s disease virus (MDV), and is characterized by the rapid onset of multifocal aggressive T-cell lymphoma in the chicken host. Although severa...

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Detalles Bibliográficos
Autores principales: Trapp-Fragnet, Laëtitia, Bencherit, Djihad, Chabanne-Vautherot, Danièle, Le Vern, Yves, Remy, Sylvie, Boutet-Robinet, Elisa, Mirey, Gladys, Vautherot, Jean-François, Denesvre, Caroline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063868/
https://www.ncbi.nlm.nih.gov/pubmed/24945933
http://dx.doi.org/10.1371/journal.pone.0100004