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Pax7 Is Necessary and Sufficient for the Myogenic Specification of CD45(+):Sca1(+) Stem Cells from Injured Muscle

CD45(+):Sca1(+) adult stem cells isolated from uninjured muscle do not display any myogenic potential, whereas those isolated from regenerating muscle give rise to myoblasts expressing the paired-box transcription factor Pax7 and the bHLH factors Myf5 and MyoD. By contrast, CD45(+):Sca1(+) isolated...

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Detalles Bibliográficos
Autores principales:	Seale, Patrick, Ishibashi, Jeff, Scimè, Anthony, Rudnicki, Michael A
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2004
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC406392/ https://www.ncbi.nlm.nih.gov/pubmed/15138500 http://dx.doi.org/10.1371/journal.pbio.0020130

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