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Many Ribosomal Protein Genes Are Cancer Genes in Zebrafish

We have generated several hundred lines of zebrafish (Danio rerio), each heterozygous for a recessive embryonic lethal mutation. Since many tumor suppressor genes are recessive lethals, we screened our colony for lines that display early mortality and/or gross evidence of tumors. We identified 12 li...

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Detalles Bibliográficos
Autores principales:	Amsterdam, Adam, Sadler, Kirsten C, Lai, Kevin, Farrington, Sarah, Bronson, Roderick T, Lees, Jacqueline A, Hopkins, Nancy
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2004
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC406397/ https://www.ncbi.nlm.nih.gov/pubmed/15138505 http://dx.doi.org/10.1371/journal.pbio.0020139

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