Genome Sequences of Two Carbapenemase-Resistant Klebsiella pneumoniae ST258 Isolates

Klebsiella pneumoniae, an ESKAPE group (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter species) pathogen, has acquired multiple antibiotic resistance genes and is becoming a serious public health threat. Here, we...

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Detalles Bibliográficos
Autores principales: Ramirez, Maria Soledad, Xie, Gang, Johnson, Shannon, Davenport, Karen, van Duin, David, Perez, Federico, Bonomo, Robert A., Chain, Patrick, Tolmasky, Marcelo E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2014
Materias:
Prokaryotes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4064024/
https://www.ncbi.nlm.nih.gov/pubmed/24948759
http://dx.doi.org/10.1128/genomeA.00558-14
Descripción
Sumario:Klebsiella pneumoniae, an ESKAPE group (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter species) pathogen, has acquired multiple antibiotic resistance genes and is becoming a serious public health threat. Here, we report the genome sequences of two representative strains of K. pneumoniae from the emerging K. pneumoniae carbapenemase (KPC) outbreak in northeast Ohio belonging to sequence type 258 (ST258) (isolates Kb140 and Kb677, which were isolated from blood and urine, respectively). Both isolates harbor a bla(KPC) gene, and strain Kb140 carries bla(KPC-2), while Kb677 carries bla(KPC-3).

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